pentobarbital will minimize the level or impact of ethotoin by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Check.
pentobarbital will minimize the level or influence of buprenorphine subdermal implant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Keep track of clients presently on buprenorphine subdermal implant who require recently-initiated therapy with CYP3A4 inducer for indications and signs or symptoms of withdrawal.
pentobarbital will decrease the extent or result of alfuzosin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.
pentobarbital will reduce the level or impact of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Potent CYP3A4 inducers are envisioned to lead to significant decreases in sildenafil plasma concentrations
If inducer is discontinued, take into consideration oliceridine dosage reduction and watch for signs of respiratory depression.
pentobarbital will minimize the extent or effect of quetiapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. here Use Caution/Keep an eye on.
pentobarbital will lessen the extent or outcome of quinidine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Reserve concomitant prescribing of those drugs in patients for whom other treatment method possibilities are insufficient. Restrict dosages and durations towards the least needed. Watch intently for indications of respiratory depression and sedation.
pentobarbital will minimize the level or outcome of budesonide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will lower the extent or influence of diclofenac by impacting hepatic enzyme CYP2C9/ten metabolism. Insignificant/Significance Unidentified.
pentobarbital will reduce the extent or influence of tinidazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Comment: Barbiturates may perhaps enhance adverse effects, like respiratory despair, made by toxic doses of TCAs. With therapeutic doses of TCAs, barbiturates increase metabolism and reduce blood concentrations of TCAs.
pentobarbital will lower the extent or effect of nilotinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will minimize the level or influence of paclitaxel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unfamiliar.